STA 290 Seminar Series
DATE: Thursday, May 25th 2017, 4:10pm
LOCATION: MSB 1147, Colloquium Room. Refreshments at 3:30pm in MSB 4110
SPEAKER: Gerald Quon, Molecular and Cellular Biology, UC Davis
TITLE: “Statistical applications in human genomics”
ABSTRACT: The study of human biology and disease is undergoing a revolution due to the ever-increasing repertoire of high throughput assays that can measure different aspects of human biology. As such, statistical approaches have been developed to address a diverse set of problems, of which I will discuss three such examples. First, I will present a graphical model to predict how disease risk is modulated by DNA sequence variation. Time permitting, I will also talk about ongoing exploratory work using variants of stochastic block models to perform joint inference of gene communities from multiple graphs, as well as zero-inflated counting models for performing dimensionality reduction on measures of genome activity.